Radiotherapy optional for older breast cancer patients, study suggests
IndependentFeb 16, 2023
According to a study published on Wednesday by the New England Journal of Medicine, more older women with low-risk breast cancer may not need to undergo radiation after breast-conserving surgery to increase their survival chances.
Results of a Phase 3 randomized trial indicate the addition of radiotherapy, alongside breast-conserving surgery and hormone therapy, makes almost no difference to the survival rates for patients over age 65 who are treated for the disease at an early stage.
These findings offer a glimmer of hope to the long-standing problem of overtreatment in women with low-risk breast cancer. While the data doesn't in any way weaken the value of radiotherapy, the study's results can potentially reduce the economic burden of radiotherapy on older patients as well as improve the quality of their lives by limiting the side-effects of their treatment.
Caution must be exercised in omitting radiation for cancer patients who may find it difficult to tolerate the side effects of hormonal therapy. Moreover, the choice to skip radiotherapy, if taken, must be tailored and customized to the patient’s disease, comorbidities, and preferences.
There is a 50% chance that the average survival rate of all cancers in the US will exceed 75% for both genders by June 2029, according to the Metaculus prediction community.