Study: E-Cigarettes Likely Cause Lung and Oral Cancer

Is vaping a dangerous health threat fueling nicotine addiction or a life-saving tool that helps smokers quit?
Study: E-Cigarettes Likely Cause Lung and Oral Cancer
Above: A teenage boy smokes a vape at a cafe in Bekasi, West Java, on Feb. 22. Image credit: Aditya Irawan/NurPhoto/Getty Images

The Facts

  • A University of New South Wales-led review published in the journal Carcinogenesis has concluded that nicotine-based e-cigarettes are likely to cause lung and oral cancer. The study analyzed peer-reviewed studies from 2017 to 2025.
  • The review drew on clinical studies, animal experiments and lab data, finding consistent evidence of DNA damage, oxidative stress, tissue inflammation and lung tumors in mice exposed to vape aerosols.
  • Lead author Adjunct Prof. Bernard Stewart said the exact number of cancer cases attributable to vaping remains unclear, noting the assessment is "qualitative and does not involve a numerical estimate of cancer risk or burden."

Sources Split


The Spin


Narrative A

Vaping is a genuine health threat that exposes users to thousands of unidentified chemicals, nicotine addiction and serious lung disease risks. E-cigarettes haven't earned FDA approval as cessation tools, and most people who try them to quit end up using both products. A new generation is getting hooked on nicotine through vaping, and that addiction pipeline leads straight to traditional tobacco use.

Narrative B

The science is settled — vaping is far less harmful than smoking, and misleading headlines have convinced smokers to stick with cigarettes instead of switching to a proven quitting tool. Cochrane Reviews show high certainty that vapes outperform patches and gums for quitting. Letting smokers believe vaping is equally dangerous is a public health failure that will cost lives.


Metaculus Prediction

© 2026 Improve the News Foundation. All rights reserved.Version 7.18.3

© 2026 Improve the News Foundation.

All rights reserved.

Version 7.18.3